Publications of Dr. Earl K. Miller, Ph.D. Picower Professor of Neuroscience, MIT

Loh, M., Pasupathy, A., Miller, E.K., and Deco, G. (2008) Neurodynamics of the prefrontal cortex during conditional visuomotor associations. Journal of Cognitive Neuroscience. 20:421-431.

Freedman, D.J. And Miller, E.K. (2008) Neural mechanisms of visual categorization: Insights from neurophysiology. Neuroscience and Biobehavioral Reviews, 32(2):311-29.

Buschman, T.J. and Miller, E.K. (2007) Top-down versus bottom-up control of attention in the prefrontal and posterior parietal cortices. Science. 315: 1860-1862 Read Robert Knight's Perspectives article about this work

Warden, M.R. and Miller, E.K. (2007) The representation of multiple objects in prefrontal neuronal delay activity. Cerebral Cortex. 17: i41-i50

Miller, E.K. and Wallis, J.D. (in press) The prefrontal cortex and executive brain functions. Fundamental Neuroscience, 3rd edition

Fusi, S., Asaad, W.F., Miller, E.K., and Wang, X.J. (2007) A neural circuit model of flexible sensori-motor mapping: Learning and forgetting on multiple timescales. Neuron. 54: 319-333.

Miller, E.K. and Wallis, J.D. (in press) Executive Control: Definitions and neural substrates. In: The New Encyclopedia of Neuroscience, Squire, Albright, Bloom, Gage, and Spitzer (Eds.), Oxford University Press.

Miller, E.K. and Buschman, T.J. (in press) Rules through recursion: How interactions between the frontal cortex and basal ganglia may build abstract, complex, rules from concrete, simple, ones. In: The Neuroscience of Rule-Guided Behavior, S. Bunge & J. Wallis (eds.), Oxford University Press.

Miller, E.K. (in press) The prefrontal cortex: categories, concepts, and cognitive control In: Memories: Molecules and Circuits, Research and Perspectives in Neurosciences, Bontempi B., Silva A.J., Christen Y. (eds), Heidelberg: Springer.

Miller, E.K. and Buschman, T.J. (in press) Bootstrapping your brain: How interactions between the frontal cortex and basal ganglia may produce organized actions and lofty thoughts. In: Neurobiology of Learning and Memory (2nd Edition), Kesner, R.P. and Martinez, J.L. (Eds), Elsevier

Histed, M.H. and Miller, E.K. (2006) Microstimulation of frontal cortex can reorder a remembered spatial sequence. Public Library of Science Biology, Vol. 4, No. 5. View commentary by Francoise Chanut

Freedman, D.J., Riesenhuber, M., Poggio, T., and Miller, E.K. (2006) Experience dependent sharpening of visual shape selectivity in inferior temporal cortex. Cerebral Cortex. 16: 1631-1644

Muhammad, R., Wallis, J.D., and Miller, E.K. (2006) A comparison of abstract rules in the prefrontal cortex, premotor cortex, the inferior temporal cortex and the striatum. Journal of Cognitive Neuroscience, 18: 974-989.

Greene, M., Schill, K., Takahasi, S., Bateman-House, A., Beauchamp, T., Bok, H., Cheney, D., Coyle, J., Deacon, T., Dennett, D., Donovan, P., Flanagan, O., Goldman, S., Greely, H., Martin, L., Miller, E., Mueller, D., Siegel, A., Solter, D., Gearhart, J., McKhann, G., and Faden, R. (2005) Moral issues of human-non-human primate neural grafting. Science, 309:385-386..

Pasupathy, A. and Miller, E.K. (2005) Different time courses for learning-related activity in the prefrontal cortex and striatum. Nature, 433:873-876.

Nieder, A. and Miller, E.K. (2005) Neural correlates of numerical cognition in the neocortex of non-human primates In: From Monkey Brain to Human Brain, S. Dehaene, J. R. Duhamel, M. Hauser & G. Rizzolatti (eds.) Cambridge, MIT Press

Nieder, A. and Miller, E.K. (2004) A parieto-frontal network for visual numerical information in the monkey. Proceedings of the National Academy of Sciences, 101:7457-7462.

Nieder, A. and Miller, E.K. (2004) Analog numerical representations in rhesus monkeys: Evidence for parallel processing. Journal of Cognitive Neuroscience. 16:889-901.

Miller, E.K. and Wallis, J.D. (2004) Volition and the prefrontal cortex. In: The Visual Neurosciences, Chalupa, L.M. and Werner, J.S. (eds.), Cambridge, MIT Press, pp 1546-1560.

Sharma, J., Dragoi, V., Tenenbaum, J.B., Miller, E.K., and Sur, M. (2003) V1 neurons signal acquisition of an internal representation of stimulus location. Science, 300:1758-1763.

Wallis, J.D. and Miller, E.K. (2003) From rule to response: neuronal processes in the premotor and prefrontal cortex. Journal of Neurophysiology, 90:1790-1806.

Wallis, J.D. and Miller, E.K. (2003) Neuronal activity in the primate dorsolateral and orbital prefrontal cortex during performance of a reward preference task. European Journal of Neuroscience. 18:2069-2081

Bunge, S.A., Kahn, I. Wallis, J.D., Miller, E.K., and Wagner, A.D. (2003) Neural circuits subserving the retrieval and maintenance of abstract rules. Journal of Neurophysiology. 90:3419-3428.

Freedman, D.J., Riesenhuber, M., Poggio, T., and Miller, E.K (2003) A comparison of primate prefrontal and inferior temporal cortices during visual categorization. Journal of Neuroscience, 23(12):5235-5246.

Miller, E.K., Nieder, A., Freedman, D.J., and Wallis, J.D. (2003) Neural correlates of categories and concepts. Current Opinion in Neurobiology. 13:2:198-203.

Miller, E.K., Freedman, D.J., and Wallis, J.D. (2003) The prefrontal cortex: categories, concepts, and cognition. In: The Physiology of Cognitive Processes, Parker, A., Derrington, A., Blakemore, C. (eds.). Oxford University Press, pp 252-273.

Nieder, A. and Miller, E.K. (2003) Coding of cognitive magnitude: Compressed scaling of numerical information in the primate prefrontal cortex. Neuron. 37:149-157. Commentary by Pessoa and Desimone Commentary in Trends in Cognitive Sciences by Dehaene

Miller, E.K. and Wallis, J.D. (2003) The prefrontal cortex and executive brain functions. In: Fundamental Neuroscience, 2nd Edition, Squire, L.R., Bloom, F.E., Roberts, J.L., Zigmond, M.J., McConnell, S.K., Spitzer, N.C. (eds.), Academic Press, pp 1353-1376.

Nieder, A., Freedman, D.J., and Miller, E.K. (2002) Representation of the quantity of visual items in the primate prefrontal cortex. Science. 297:1708-1711 News and Views summary by Dehaene Read News Articles about this (and other) work

Miller, E.K., Freedman, D.J., and Wallis, J.D. (2002) The prefrontal cortex: categories, concepts, and cognition. Philosophical Transactions: Biological Sciences. 357:1123-1136.

Duncan, J. and Miller, E.K. (2002) Cognitive focusing through adaptive neural coding in the primate prefrontal cortex. In: Principles of Frontal Lobe Function, Stuss, D. and Knight, R.T. (eds.), Oxford University Press, pp 278-291.

Freedman, D.J., Riesenhuber, M., Poggio, T., and Miller, E.K. (2002) Visual categorization and the primate prefrontal cortex: Neurophysiology and behavior. Journal of Neurophysiology, 88, 914-928 View cover art

Dragoi, V., Sharma, J., Miller, E.K., and Sur, M. (2002) Dynamics of neural sensitivity in primate V1 underlying local feature discrimination. Nature Neuroscience.

Rainer, G. and Miller, E.K. (2002) Timecourse of object-related activity in the primate prefrontal cortex during a short-term memory task. European Journal of Neuroscience, 15, 1244-1254.

Miller, E.K. and Asaad, W.F. (2002) The prefrontal cortex: conjunction and cognition. In: Handbook of Neuropsychology, 2nd Edition, Vol. 7: The Frontal Lobes, Grafman, J. (Ed.). Elsevier.

Wallis, J.D., Anderson, K.C., and Miller, E.K. (2001) Single neurons in the prefrontal cortex encode abstract rules. Nature, 411:953-956. Read MIT press release

Freedman, D.J., Riesenhuber, M., Poggio, T., and Miller, E.K. (2001) Categorical representation of visual stimuli in the primate prefrontal cortex. Science, 291:312-316. Read an MSNBC article about this work NY Times on the Web ABCNews.com MIT press release Nature news article (PDF)

Miller, E.K. and Cohen, J.D. (2001) An integrative theory of prefrontal cortex function. Annual Review of Neuroscience, 24:167-202.

Chelazzi, L., Miller, E.K., Duncan, J., and Desimone, R. (2001) Responses of neurons in macaque area V4 during memory-guided visual search. Cerebral Cortex, 11:761-762.

Miller, E.K. (2000) The prefrontal cortex and cognitive control. Nature Reviews Neuroscience, 1:59-65.

Rainer, G. and Miller, E.K. (2000) Effects of visual experience on the representation of objects in the prefrontal cortex. Neuron, 27:179-189. View abstract and cover image. Read a Highlight about this article in Nature Reviews Neuroscience. News and Views by Sekuler and Bennett

Asaad, W.F., Rainer, G., Miller, E.K. (2000) Task-specific neural activity in the primate prefrontal cortex. Journal of Neurophysiology, 84:451-459

Rainer G. and Miller, E.K. (2000) Neural ensemble states in prefrontal cortex identified using a hidden markov model with a modified EM algorithm, Neurocomputing, 32-33: 961-966.

Miller, E.K. (2000) The neural basis of the top-down control of visual attention in the prefrontal cortex. In: Control of Cognitive Processes: Attention and Performance 18, Monsell, S. and Driver, J. (eds.), pp 511-534, MIT Press, Cambridge. Buy it from Amazon.com Buy it from MIT Press

Miller, E.K. (2000) The prefrontal cortex: no simple matter (Commentary). Neuroimage, 11:447-450.

Miller, E.K. (2000) Organization through experience (News and Views). Nature Neuroscience, 3:1066-1068.

Rainer, G., Rao, S.C., and Miller, E.K. (1999) Prospective coding for objects in the primate prefrontal cortex. Journal of Neuroscience, 19:5493-5505.

Miller, E.K. (1999) The prefrontal cortex: Complex neural properties for complex behavior. Neuron, 22:15-17.

Miller, E.K. (1999) Prefrontal cortex and the neural basis of executive functions. In: Attention, space, and action: Studies in cognitive neuroscience, Humphreys, G.W, Duncan, J., and Treisman, A.M. (eds.) Oxford University Press, Oxford. pp 251-272.

Miller, E.K. (1999) Straight from the top (News and Views). Nature, 401, 650-651.

Rainer, G., Asaad, W.F., and Miller, E.K. (1998) Selective representation of relevant information by neurons in the primate prefrontal cortex. Nature, 393:577-579.

Asaad, W.F., Rainer, G. and Miller, E.K. (1998) Neural activity in the primate prefrontal cortex during associative learning. Neuron, 21:1399-1407.

Rainer, G., Asaad, W.F., and Miller, E.K. (1998) Memory fields of neurons in the primate prefrontal cortex. Proceedings of the National Academy of Sciences, 95:15008-15013.

Chelazzi, L., Duncan, J., Miller, E.K., and Desimone, R. (1998) Responses of neurons in inferior temporal cortex during memory-guided visual search. Journal of Neurophysiology, 80:2918-2940.

Rao, S.C., Rainer, G., and Miller, E.K. (1997) Integration of what and where in the primate prefrontal cortex. Science, 276:821-824.

Suzuki, W.A., Miller, E.K. and Desimone R. (1997) Object and place memory in the macaque entorhinal cortex. Journal of Neurophysiology. 78:1062-1081.

Miller, E.K., Erickson, C.A., and Desimone, R. (1996) Neural mechanisms of visual working memory in prefrontal cortex of the macaque. Journal of Neuroscience. 16:5154-5167

Miller, E.K. (1995) Neocortical mechanisms for visual memory. In: Scale in Conscious Experience: Is the brain too important to be left to biologists to study?, Pribram, K. and King, J. (eds.) Lawrence Erlbaum, London, 105-115.

Desimone, R., Miller, E.K., Chelazzi, L., and Lueschow, A. (1995) Multiple memory systems in the visual cortex. In: The Cognitive Neurosciences, Gazzaniga, M. (ed.) MIT Press, Cambridge, MA, 475-486.

Desimone, R., Chelazzi, L., Miller, E.K., and Duncan, J. (1995) Neuronal mechanisms of visual attention. In: Linking Psychophysics, Neurophysiology, and Computational Vision, Papathomas, T.V., Chubb, C., Gorea, A., and Kowler, E. (eds.) MIT Press, Cambridge, MA, 219-226.

Miller, E.K. and Desimone, R. (1994) Parallel neuronal mechanisms for short-term memory. Science 263:520-522.

Lueschow, A., Miller, E.K., and Desimone, R. (1994) Inferior temporal mechanisms for invariant object recognition. Cerebral Cortex 5:523-531.

Miller, E.K. (1994) Neocortical memory traces. A commentary on "Two functional components of the hippocampal memory system" by Eichenbaum, Otto, and Cohen. Behavioral Brain Sciences 17:488-489.

Desimone, R., Chelazzi, L., Miller, E.K., and Duncan, J. (1994) Neural mechanisms for memory-guided visual search. In: Structural and Functional Organization of the Neocortex, Albowitz, A., Albus, A., Kuhnt, U., Nothdurft, H.C., and Wahle, P. (eds.) Springer-Verlag, Berlin, 279-285.

Desimone, R., Miller, E.K., and Chelazzi, L. (1994) The interaction of neural systems for attention and memory. In: Large-Scale Theories of the Brain, Koch, C. and Davis, J.L. (eds.) MIT Press, Cambridge, MA, 75-91.

Chelazzi, L., Miller, E.K., Duncan, J., and Desimone, R. (1993) A neural basis for visual search in inferior temporal (IT) cortex. Nature 363:345-347.

Miller, E.K. and Desimone, R. (1993) Scopolamine affects short-term memory but not inferior temporal neurons. NeuroReport 4:81-84.

Miller, E.K., Li, L., and Desimone, R. (1993) Activity of neurons in anterior inferior temporal cortex during a short-term memory task. Journal of Neuroscience 13:1460-1478.

Li, L., Miller, E.K., and Desimone, R. (1993) The representation of stimulus familiarity in anterior inferior temporal cortex. Journal of Neurophysiology 69:1918-1929.

Miller, E.K., Gochin, P.M., and Gross, C.G. (1993) Suppression of visual responses of neurons in inferior temporal cortex of the awake macaque by addition of a second stimulus. Brain Research 616:25-29.

Miller, E.K., Li, L., and Desimone, R. (1991) A neural mechanism for working and recognition memory in inferior temporal cortex. Science 254:1377-1379.

Gochin, P.M., Miller, E.K., Gross, C.G., and Gerstein, G.L. (1991) Functional interactions among neurons in inferior temporal cortex of the awake macaque. Experimental Brain Research 84:505-516.

Miller, E.K., Gochin, P.M., and Gross, C.G. (1991) A habituation-like decrease in the responses of neurons in inferior temporal cortex of the macaque. Visual Neuroscience 7:357-362